Case Study.

PCOS Case Study

Meet Aaliyah, a patient since 2023.

When Aaliyah (female, 40’s) joined Index Health, she was struggling with PCOS, Metabolic Syndrome, and IBS-C. Her goals for partnering with us included improving her metabolism, increasing her energy levels throughout the day, reducing her risk of developing CAD, and fixing her digestive issues.
While this patient’s name and photo have been changed to protect her anonymity, she agreed to share her results here so that future clients can see what to expect from working with Index Health.

Results After 7 Months.

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Medical Data.

Lab Marker
Initial Result
Improved Result
Healthy Range

IR score (assesses insulin resistance level and diabetes risk)



< 1

Elastase (digestive enzymes made by pancreas needed to  digest food)



> 200

Fecal sIgA (high levels of SIgA may indicate an infection of the digestive system)



0 - 680

ALT (high levels of ALT may be a sign of a liver injury or disease)



4 - 36




< 80

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Results Summary.

  • Significant reduction in Insulin resistance.
  • Improved gastrointestinal health with  better pancreatic function and lower immune activation.
  • Reduction in cardiovascular risk with lower ApoB.
  • Improved liver function after reduction in unnecessary supplementation.

Initial Diagnosis.

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  • Polycystic ovarian syndrome
  • Strong family hx of CAD
  • Gut health symptoms that began in 2015
  • Hormone health
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Meds & Supplements.

  • Flonase
  • Supplements: Total of 23, notable for a variety of antifungal, antiviral, herbal antimicrobial options
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Health Goals.

  • Gut health improvement
  • Hormone health
  • Kidney health
  • Decrease stress

Treatment & Personalized Plan.

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Lab Results.

  • ALT elevated at 34, after removal of supps down to 18
  • CBC with acanthocytes/platelet clumping (seen by hematology)
  • EBV titers suggestive of reactivation
  • Very high 2/16 OH-E1 ratio, poor methylation
  • Gut Health testing shows low elastase, high sIgA, presence of heavy growth of a potential pathogen (Klebsiella oxytoca), also lesser growth of Citrobacter and Klebsiella pneumoniae
  • Genomics insights: VDR +/+, PAI-1 +/+ (4G/4G), Absent GSTM-1, CYP1A1 +/- (hyperinduction, caution PAHs/HCAs)
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Meds & Supplement Changes.

  • Strategy to remove supplements from 23 → 9.
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Lifestyle Changes.

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Nutrition Plan.

  • Dairy as a condiment
  • Lower temp cooking due to GSTM/CYP1A1 combo, using herbs on meat for absorptive capacity (HCAs/PAHs)
  • CORE meal plan
  • Resources for gluten-free recipes
  • Avoid fasted workouts
  • Breathwork and stress reduction techniques offered

Ready to begin your journey to better health?

After reading the above PCOS case study, you can see what great results this patient had in improving her health and quality of life. Index Health can help you to relieve your symptoms and improve your health.

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